Is hydrogen rich water good for you?

New SPE+PEM High ORP Hydrogen Generator Water Ionizer Bottle with Japan electrolysis technology

 Our Hydrogen Water Bottle Special Advantages:
1.Puts only pure H2 into the water. Oxygen, Ozone and Chlorine are separated out.
2.Unlimited Water Quality,any kind of water can be used.
3.Generates much higher concentration of hydrogen water than standard electrolysis bottles.
4. Dual Use Design,able to attach disposable plastic drinking water bottles,save space for backbag for for travel, work and office.(Note: Only suitable for universal mineral water bottleneck inner diameter 26mm.)
5. 1400mAh large capacity battery

$285.00 Original price was: $285.00.$199.00Current price is: $199.00.

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Effectiveness of Hydrogen Rich Water on Antioxidant Status of Subjects with Potential Metabolic Syndrome — Atsunori Nakao (Heart, Lung and Esophageal Surgery Institute, Department of Surgery, University of Pittsburgh Medical Center) , Yoshiya Toyoda (Heart, Lung and Esophageal Surgery Institute, Department of Surgery, University of Pittsburgh Medical Center ), Prachi Sharma (KGK Synergize, Inc.), Malkanthi Evans (KGK Synergize, Inc.), Najla Guthrie (KGK Synergize, Inc.)

An Open Label Pilot Study Results found that Metabolic syndrome is characterized by cardiometabolic risk factors that include obesity, insulin resistance, hypertension and dyslipidemia. Oxidative stress is known to play a major role in the pathogenesis of metabolic syndrome. The objective of this study was to examine the effectiveness of hydrogen rich water (1.5–2 L/day) in an open label, 8-week study on 20 subjects with potential metabolic syndrome. Hydrogen rich water was produced, by placing a metallic magnesium stick into drinking water (hydrogen concentration; 0.55–0.65 mM), by the following chemical reaction; Mg + 2H₂O → Mg (OH)₂ + H₂. The consumption of hydrogen rich water for 8 weeks resulted in a 39% increase (p<0.05) in antioxidant enzyme superoxide dismutase (SOD) and a 43% decrease (p<0.05) in thiobarbituric acid reactive substances (TBARS) in urine. Further, subjects demonstrated an 8% increase in high density lipoprotein (HDL)-cholesterol and a 13% decrease in total cholesterol/HDL-cholesterol from baseline to week 4. There was no change in fasting glucose levels during the 8 week study. In conclusion, drinking hydrogen rich water represents a potentially novel therapeutic and preventive strategy for metabolic syndrome. The portable magnesium stick was a safe, easy and effective method of delivering hydrogen rich water for daily consumption by participants in the study.

Articles from jstage Japan.

References (30)

• [1] Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., and Shimomura, I.: Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest., 114, 1752–1761, 2004.
• [2] Holvoet, P., Lee, D.H., Steffes, M., Gross, M., and Jacobs, D.R.Jr.: Association between circulating oxidized low-density lipoprotein and incidence of the metabolic syndrome. JAMA, 299, 2287–2293, 2008.
• [3] Ford, E.S., Giles, W.H., and Dietz, W.H.: Prevalence of the metabolic syndrome among US adults: findings from the third National Health and Nutrition Examination Survey. JAMA, 287, 356–359, 2002.
• [4] Grundy, S.M., Brewer, H.B. Jr., Cleeman, J.I., Smith, S.C.Jr., and Lenfant, C.: Definition of metabolic syndrome: Report of the National Heart, Lung, and Blood Institute/American Heart Association conference on scientific issues related to definition. Circulation, 109, 433–438, 2004.
• [5] Dean, R.T., Fu, S., Stocker, R., and Davies, M.J.: Biochemistry and pathology of radical-mediated protein oxidation. Biochem. J., 324, 1–18, 1997.
• [6] Halliwell, B., Gutteridge, J.M., and Cross, C.E.: Free radicals, antioxidants, and human disease: where are we now?. J. Lab. Clin. Med., 119, 598–620, 1992.
• [7] Ford, E.S., Mokdad, A.H., Giles, W.H., and Brown, D.W.: The metabolic syndrome and antioxidant concentrations: findings from the Third National Health and Nutrition Examination Survey. Diabetes, 52, 2346–2352, 2003.
• [8] Villeponteau, B., Cockrell, R., and Feng, J.: Nutraceutical interventions may delay aging and the age-related diseases. Exp. Gerontol., 35, 1405–1417, 2000.
• [9] Halliwell, B.: Reactive oxygen species in living systems: source, biochemistry, and role in human disease. Am. J. Med., 91, 14S–22S, 1991.
• [10] Ohsawa, I., Ishikawa, M., Takahashi, K., Watanabe, M., Nishimaki, K., Yamagata, K., Katsura, K., Katayama, Y., Asoh, S., and Ohta, S.: Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nat. Med., 13, 688–694, 2007.
• [11] Buchholz, B.M., Kaczorowski, D.J., Sugimoto, R., Yang, R., Wang, Y., Billiar, T.R., McCurry, K.R., Bauer, A.J., and Nakao, A.: Hydrogen inhalation ameliorates oxidative stress in transplantation induced intestinal graft injury. Am. J. Transplant., 8, 2015–2024, 2008.
• [12] N.A.S.A.: Safety Standard for Hydrogen and Hydrogen Systems. National Aeronautics and Space Administration, 2005.
• [13] Ohsawa, I., Nishimaki, K., Yamagata, K., Ishikawa, M., and Ohta, S.: Consumption of hydrogen water prevents atherosclerosis in apolipoprotein E knockout mice. Biochem. Biophys. Res. Commun., 377, 1195–1198, 2008.
• [14] Nakashima-Kamimura, N., Mori, T., Ohsawa, I., Asoh, S., and Ohta, S.: Molecular hydrogen alleviates nephrotoxicity induced by an anti-cancer drug cisplatin without compromising anti-tumor activity in mice. Cancer. Chemother. Pharmacol., 64, 753–761, 2009.
• [15] Sato, Y., Kajiyama, S., Amano, A., Kondo, Y., Sasaki, T., Handa, S., Takahashi, R., Fukui, M., Hasegawa, G., Nakamura, N., Fujinawa, H., Mori, T., Ohta, M., Obayashi, H., Maruyama, N., and Ishigami, A.: Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice. Biochem. Biophys. Res. Commun., 375, 346–350, 2008.
• [16] Cardinal, J.S., Zhan, J., Wang, Y., Sugimoto, R., Tsung, A., McCurry, K.R., Billiar, T.R., and Nakao, A.: Oral administration of hydrogen water prevents chronic allograft nephropathy in renal transplantation. Kidney Int., 2009, in press.
• [17] Kajiyama, S., Hasegawa, G., Asano, M., Hosoda, H., Fukui, M., Nakamura, N., Kitawaki, J., Imai, S., Nakano, K., Ohta, M., Adachi, T., Obayashi, H., and Yoshikawa, T.: Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2 diabetes or impaired glucose tolerance. Nutr. Res., 28, 137–143, 2008.
• [18] Yagi, K.: Simple procedure for specific assay of lipid hydroperoxides in serum or plasma. Methods. Mol. Biol., 108, 107–110, 1998.
• [19] Loft, S., Fischer-Nielsen, A., Jeding, I.B., Vistisen, K., and Poulsen, H.E.: 8-Hydroxydeoxyguanosine as a urinary biomarker of oxidative DNA damage. J. Toxicol. Environ. Health., 40, 391–404, 1993.
• [20] Kinnula, V.L. and Crapo, J.D.: Superoxide dismutases in the lung and human lung diseases. Am. J. Respir. Crit. Care. Med., 167, 1600–1619, 2003.
• [21] Noor, R., Mittal, S., and Iqbal, J.: Superoxide dismutase—applications and relevance to human diseases. Med. Sci. Monit., 8, RA210–215, 2002.
• [22] Fukai, T., Folz, R.J., Landmesser, U., and Harrison, D.G.: Extracellular superoxide dismutase and cardiovascular disease. Cardiovasc. Res., 55, 239–249, 2002.
• [23] Batiste, M.C. and Schaefer, E.J.: Diagnosis and management of lipoprotein abnormalities. Nutr. Clin. Care, 5, 115–123, 2002.
• [24] Whitfield, J.B.: Gamma glutamyl transferase. Crit. Rev. Clin. Lab. Sci., 38, 263–355, 2001.
• [25] Lee, D.H., Blomhoff, R., and Jacobs, D.R.Jr.: Is serum gamma glutamyltransferase a marker of oxidative stress? Free Radic. Res., 38, 535–539, 2004.
• [26] Schwertner, H.A., Jackson, W.G., and Tolan, G.: Association of low serum concentration of bilirubin with increased risk of coronary artery disease. Clin. Chem., 40, 18–23, 1994.
• [27] Madhavan, M., Wattigney, W.A., Srinivasan, S.R., and Berenson, G.S.: Serum bilirubin distribution and its relation to cardiovascular risk in children and young adults. Atherosclerosis, 131, 107–113, 1997.
• [28] Tenhunen, R., Marver, H.S., and Schmid, R.: The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase. Proc. Natl. Acad. Sci. U.S.A., 61, 748–755, 1968.
• [29] Otterbein, L.E., Soares, M.P., Yamashita, K., and Bach, F.H.: Heme oxygenase-1: unleashing the protective properties of heme. Trends. Immunol., 24, 449–455, 2003.
• [30] Dilsiz, N., Olcucu, A., Cay, M., Naziroglu, M., and Cobanoglu, D.: Protective effects of selenium, vitamin C and vitamin E against oxidative stress of cigarette smoke in rats. Cell Biochem. Funct., 17, 1–7, 1999.